This document specifies requirements and the means for their verification for the design and performance of aerial fixed wing and rotary aircraft spray systems for agriculture, forestry, turf, and vegetation control in transport access ways (such as gas and electric lines) with regard to minimizing the potential risk of environmental contamination during use, including misuse foreseeable by the manufacturer. It is intended to be used with ISO 16119-1, which gives general requirements common to all the sprayer types covered by ISO 16119. When requirements of this document are different from those stated in ISO 16119-1, the requirements of this document take precedence over the requirements of ISO 16119-1 for machines within the scope of this document. This document does cover safety of aerial spray equipment not covered by ISO 4254 series. This document is not applicable to sprayers manufactured before the date of its publication, or unmanned aerial vehicles (such as drones).